Nervous System MEchanical Basis/Jeff’s Story Autonomic Nervous System and Immune System Interactions Modulation of the immune system by the autonomic nervous system and its implication in immunological changes after training. The autonomic nervous system as a communication channel between the brain and the immune system. The sympathetic nerve–an integrative interface between two supersystems: the brain and the immune system. Potential use of drugs that target neural-immune pathways in the treatment of rheumatoid arthritis and other autoimmune diseases. It takes nerve to tell T and B cells what to do. Share this: Click to share on X (Opens in new window) X Click to share on Facebook (Opens in new window) Facebook Like Loading...